Yohimbine
A controversial aphrodisiac with environmental and side-effect issues.
Yohimbine (Yohimbe) - other names for Yohimbe: Corynanthe yohimbe, johimbe, Pausinystalia yohimbe, Yohimbi (Fr)
Yohimbine is an alkaloid which occurs naturally in the evergreen tree [1] Pausinystalia yohimbe (Yohimbe) - which is native to Nigeria, Cameroon and possibly other West African countries. Yohimbine also occurs in the plant Rauwolfia serpentina (Indian Snakeroot), and in the Chilean tree Aspidosperma quebracho [11].
Yohimbine is one of the few substances derived from herbs which seems to have been accepted, generally, by science as having actual aphrodisiac effects. It is an FDA-approved medicine for impotence. [10] Yohimbine, standardized as Yohimbine hydrochloride, has had use in prescription medicine for the treatment of erectile dysfunction. [2]
Yohimbine - History
There is little mention of Yohimbe in Western literature prior to the 20th century. Yohimbine Hydrochloride was clearly in use as an aphrodisiac by 1902 - as I found an advertisement offering it "for male impotence" in Pharmazeutische Zentralhalle für Deutschland, Volume 43 [3] of that year.
The first scientific reference I can find to claims of aphrodisiac quality is from a 1916 vetinary paper investigating Muira Puama in Pamphlets on Biology: Kofoid collection, Volume 472 [4] which states (translated from German using Google Translate):
Drugs which stimulate the sex drive, have been long in use. In veterinary medicine the cantharides was formerly used almost exclusively for this purpose. For several decades we have come to know but especially effective means, some of which are recommended in human medicine, but their use for veterinary medicine is almost always too expensive. It should be mentioned as example the yohimbine, Yopuamol, Impotan, Potentan, Potentol, Libidol, Virisanol, Puamambra and last but not the Muiracithin, means that almost all mixtures of known aphrodisiacs, namely the extractives of the bark of the Corynanthe Yohimbe Muira Puama and with lecithin and similar devices represent.
The online translator does a rough job, but we can nonetheless make enough sense of this translation to deduce that Yohimbine was known to medical practice in the 19th century. In the 20th century, much work appears on Yohimbine.
Yohimbine chemical structure
Yohimbe and the environment
Yohimbe supplements, and yohimbine (the alkaloid) are typically made from the bark of the Pausinystalia yohimbe tree. However, a tree stripped of its bark will die - and it takes over 10 years for the tree to grow to a size which makes it valuable. Yohimbe trees are often found in poor countries such as Nigeria - and the tree, in native rainforest, has an average population density of around 5 trees per hectare. [10]
In short, what this means is that the poor trees don't stand a chance. As a result of the plunder triggered by the high demand from the herbal products / pharmaceutical trade, Pausinystalia yohimbe is now an uncommon plant in Nigeria. It has also become rare in Cameroon, which was the main supplier even as recently as the 1990's. [5] Some plantations have now begun to be established and the responsible consumer is encouraged to question whether the material being purchased is plantation sourced. However, much of the Yohimbe supplied is said not to be from sustainable sources. [10]
Yohimbe quality
As a result of both the scarcity and potential side effects of Yohimbine, "pseudo Yohimbe" has been sold to the supplement industry. Either that, or some of the yohimbe bark products contain such a small amount of the alkaloid yohimbine, that neither any beneficial nor any adverse affects are felt! [5]
Is Yohimbine an Aphrodisiac?
Several scientific studies have shown strong indicators of aphrodisiac qualities with Yohimbine, and it appears to be one of the plants more widely accepted as aphrodisiac. A 2003 study showed that Yohimbine reversed sexual satiety in male rats. [6]
Yohimbine / Yohimbe bark is included in a wide variety of "sexual enhancement" type formulas - although some formulas give two options, "with" and "without" Yohimbe, for reasons as will be seen below. Yohimbe is listed (as Pausinystalia johimbe) in the AHPA's "Herbs of Commerce", p.107 [7]
Yohimbine Side Effects
Note - this is not medical advice, it is just reportage of information found on other web sites.
Significant side effects have in some cases been noted from Yohimbine - including anxiety reactions, rapid heart rate, high blood pressure and insomnia.
The "dosage range" is narrow - in other words, the range between an effective and a dangerous dose is small. It is said that Yohimbine can be dangerous if used excessively. It should not be used by anyone with liver, kidney, heart disease, pregnancy or a psychological disorder. [1] [8]
I also found a document listing several interactions with other medicines, notably Tricyclic Antidepressants [8] [9]
In summary - numerous yohimbe bark supplements are widely available, and there is a body of strong evidence to support yohimbine's enhancement to sexual function. However, with environmental concerns, purity concerns and side effect concerns; over here at aphrodisiacs-info.com , this researcher imagines that it might be a good idea to consider other options... of which there are many.
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Sources:
[1] http://www.nutriherb.net/yohimbe.html
[2] http://en.wikipedia.org/wiki/Yohimbine
[3] http://books.google.com/books?id=K1VLAAAAMAAJ
[4] http://books.google.com/books?id=8DMXAQAAIAAJ
[5] http://www.yohimbe.org
[6] http://www3.interscience.wiley.com/journal/118874269/abstract
[7] "Herbs of Commerce" (AHPA) (2000 edition) - Michael McGuffin, John T. Kartesz, Albert Y Leung, Arthur O. Tucker p.249
[8] http://www.mskcc.org/mskcc/html/69423.cfm
[9] http://home.caregroup.org/clinical/altmed/interactions/Herbs/Pausinystalia_y.htm
[10] http://www.diet-and-health.net/Naturopathy/Yohimbe.html
[11] http://www.ncbi.nlm.nih.gov/pubmed/12050513
Note - the information on this website is not medical advice, is not a substitute for medical consultation, has not been evaluated by the FDA and is not intended to diagnose, treat, cure any disease. Please seek advice from a medical professional if you have symptoms, are concerned about your health, or before using supplements or aphrodisiac products.
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